Pharmacology USMLE Questions: Toxicology Antidotes – Organophosphates, Acetaminophen and Methanol

Poisonings and their antidotes are reliable points on USMLE Step 1. The exam often asks for the mechanism of the antidote, not just its name. Here are three practice questions. Pick your answer first, then open the explanation. Question 1: A farmer with pinpoint pupils, drooling and muscle twitching A 45-year-old farmer is brought to … Read more

Pharmacology USMLE Questions: Diuretics – Thiazides, Ethacrynic Acid and Spironolactone

Diuretics are tested on USMLE Step 1 through their site of action, their electrolyte effects and their side effects. If you know where each one acts in the nephron, most questions become easy. Pick your answer first, then open the explanation. Question 1: A diuretic that raises calcium and glucose A 60-year-old woman with hypertension … Read more

Pharmacology USMLE Questions: Doxorubicin, Sildenafil, Clopidogrel, Phenytoin and More

These seven pharmacology questions cover high-yield topics that USMLE Step 1 tests again and again: drug toxicities, drug interactions, pharmacokinetics, autonomic drugs and teratogens. Pick your answer first, then open the explanation. Question 1: Heart failure after chemotherapy A 58-year-old woman completed chemotherapy for breast cancer 8 months ago. She now has shortness of breath … Read more

USMLE Step 1 Questions: Rapid-Acting Insulin, Neurofibromatosis Type 2 and Lead Poisoning

Three USMLE Step 1 questions on insulin types, a genetic tumor syndrome and a classic toxicology sign. Pick your answer first, then open the explanation. Question 1: Which insulin is rapid-acting? A 12-year-old boy is diagnosed with type 1 diabetes and started on insulin. Which one of the following is a rapid-acting insulin? A. AspartB. … Read more

Pharmacology USMLE Questions: Aspirin Toxicity, Furosemide and Fluoxetine

Three high-yield USMLE Step 1 pharmacology questions on classic drug side effects and drug choice: aspirin toxicity, drug-induced hypokalemia and the treatment of bulimia nervosa. Pick your answer first, then open the explanation. Question 1: Which symptom is a sign of aspirin toxicity? Which of the following symptoms is known to be related to aspirin … Read more

Pharmacology USMLE Questions: Clonidine, Cimetidine and Tachyphylaxis

Three USMLE Step 1 pharmacology questions on a centrally acting antihypertensive, a classic H2-blocker side effect and an important pharmacology definition. Pick your answer first, then open the explanation. Question 1: Which antihypertensive acts on the central vasomotor center? Which of the following drugs reduces blood pressure by acting centrally on the vasomotor center? A. … Read more