USMLE Step 2 CK Neurology Questions: Acute Ischemic Stroke, Subarachnoid Hemorrhage and Giant Cell Arteritis

Neurology emergencies on USMLE Step 2 CK test time-sensitive decisions: when to give thrombolytics, which test to order after a normal CT, and when to treat before the diagnosis is confirmed. Try these three questions. Question 1: Sudden weakness and trouble speaking A 67-year-old man is brought to the emergency department 2 hours after the … Read more

USMLE Step 1 Physiology Questions: Acid-Base Disorders – Vomiting, Aspirin Overdose and Diarrhea

Acid-base questions appear on every USMLE Step 1 exam. Use the same steps every time: pH, then the primary disorder, then expected compensation, then the anion gap. Try these three questions, then open the explanations. Question 1: Several days of vomiting A 34-year-old woman has had repeated vomiting for 4 days due to a viral … Read more

USMLE Step 2 CK Psychiatry Questions: Neuroleptic Malignant Syndrome, Serotonin Syndrome and Lithium Toxicity

Psychiatric medication emergencies are high-yield on USMLE Step 2 CK. Neuroleptic malignant syndrome and serotonin syndrome look similar, so the exam tests the features that separate them, plus drug interactions that cause lithium toxicity. Try these three questions. Question 1: Fever and “lead-pipe” rigidity after starting an antipsychotic A 28-year-old man with schizophrenia was started … Read more

Pathology USMLE Questions: Anemias – Beta-Thalassemia Minor, Vitamin B12 Deficiency and Hereditary Spherocytosis

Anemia questions on USMLE Step 1 start with the MCV (microcytic, normocytic or macrocytic) and then ask you to pick the right lab finding or underlying defect. Here are three practice questions. Pick your answer first, then open the explanation. Question 1: Very small red cells with normal iron studies A 24-year-old woman of Mediterranean … Read more

USMLE Step 2 CK Pediatrics Questions: Pyloric Stenosis, Intussusception and Midgut Volvulus

Vomiting in an infant is a common USMLE Step 2 CK scenario. The age, whether the vomit is bilious, and the stool findings point to the diagnosis, and the exam asks for the next best step. Try these three questions. Question 1: A 4-week-old with forceful vomiting after every feed A 4-week-old firstborn boy has … Read more

USMLE Step 1 Immunology Questions: Hypersensitivity Reactions – Types II, III and IV

Hypersensitivity reactions are one of the most reliable Immunology topics on USMLE Step 1. You need to match each clinical picture to its mechanism: IgE, antibody against cells, immune complexes or T cells. Pick your answer first, then open the explanation. Question 1: Dark urine and swelling two weeks after a sore throat An 8-year-old … Read more