USMLE Practice Questions with Explanations

Free USMLE Step 1 and Step 2 CK practice questions with clear answers and explanations, written by Dr. Ray Makar, MD, a physician with 20 years of clinical practice who passed the USMLE himself as an international medical graduate.

Step 1 Questions  Step 2 CK Questions

Browse questions by subject

  • USMLE Step 1 – basic sciences: pharmacology, pathology, physiology and more
  • USMLE Step 2 CK – clinical knowledge: diagnosis and management
  • Pharmacology – drug mechanisms, side effects and toxicities
  • Pathology – disease mechanisms and classic presentations
  • Dermatology – skin diseases, blistering disorders, skin cancer and drug eruptions, written by a dermatologist

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How to use this site

  1. Answer first. Read the question and pick your answer before opening the explanation.
  2. Read every explanation. Learn why the right answer is right and why the others are wrong.
  3. Come back often. New questions are added regularly, focused on concepts that appear on the exam again and again.

About Dr. Ray Makar

I graduated from medical school in 1982, practiced as a dermatologist for 20 years, and passed the USMLE as a foreign medical graduate after moving to the United States. I know how hard this exam is, especially for international graduates, and I built this site to make your preparation easier. Read more about me →

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This website is for exam preparation and education only. It is not medical advice and is not affiliated with the USMLE, NBME or FSMB.