Pathology USMLE Questions: Anemias – Beta-Thalassemia Minor, Vitamin B12 Deficiency and Hereditary Spherocytosis

Anemia questions on USMLE Step 1 start with the MCV (microcytic, normocytic or macrocytic) and then ask you to pick the right lab finding or underlying defect. Here are three practice questions. Pick your answer first, then open the explanation. Question 1: Very small red cells with normal iron studies A 24-year-old woman of Mediterranean … Read more

USMLE Step 1 Questions: Rapid-Acting Insulin, Neurofibromatosis Type 2 and Lead Poisoning

Three USMLE Step 1 questions on insulin types, a genetic tumor syndrome and a classic toxicology sign. Pick your answer first, then open the explanation. Question 1: Which insulin is rapid-acting? A 12-year-old boy is diagnosed with type 1 diabetes and started on insulin. Which one of the following is a rapid-acting insulin? A. AspartB. … Read more

Pathology USMLE Questions: Boerhaave Syndrome, Hodgkin Lymphoma and Glioblastoma

Three high-yield USMLE Step 1 pathology questions: esophageal rupture after vomiting, a lymphoma with CD15 and CD30, and the most common malignant brain tumor in adults. Pick your answer first, then open the explanation. Question 1: Chest pain after vomiting with subcutaneous emphysema An alcoholic patient presents with sudden chest pain, cough and shortness of … Read more

USMLE Step 1 Questions: Steroid Osteoporosis, Breast Biopsy and Scoliosis

Three USMLE Step 1 questions covering glucocorticoid-induced osteoporosis, breast lesions that raise cancer risk, and spinal deformities. Pick your answer first, then open the explanation. Question 1: Why do corticosteroids cause osteoporosis? Which of the following is one of the reasons that corticosteroid therapy may lead to osteoporosis? A. Corticosteroids decrease renal phosphate excretionB. Corticosteroids … Read more