A 21 year-old man is admitted for bacterial meningitis. The patient has severe headache and blurred vision. His housemates report that he had gait disturbance and repeated falls on his way to the hospital. CT scan of the head reveals enlarged ventricles.
What is the mechanism of enlarged ventricle in this patient?
A- Increased production of CSF
B- Destruction of the grey matter
C- White matter disease
D- Impaired resorption of CSF
E- Obstruction of the aqueduct
Meningitis, as its name tells, is inflammation of the meninges which includes dura mater and arachnoid mater. The arachnoid granulations, which are responsible for CSF resorption are outgrowths of arachnoid mater through the dura mater. Inflammation causes obstruction of CSF resorption leading to enlarged ventricles.