A 9-year-old boy complains of difficulty breathing when he plays with other kids. Obstetric history reveals that he was delivered premature and his mother was diagnosed with rubella during pregnancy. Physical examination reveals continuous machinery murmur on the second intercostal space at the left parasternal border.

What is the treatment could be used in infants to reduce the occurrence of this condition?

A- Amphetamine

B- Atropine

C- Indomethacin

D- Prostaglandins I2

E- Prostaglandins E2


This is a case of ductus arteriosus. In infancy treatment with indomethacin result in closure of the patent duct between aorta and pulmonary artery.

The correct answer is C