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1- Causes of low PLATELETS thrombocytopenia:

Platelets Problems as TTP, ITP, DIC

Leukemia

Anemia

Trauma

Enlarged spleen

Liver disease

Ethanol

Toxins as aspirin toxicity, chemotherapy, benzene

Sepsis




2- Causes of PinPoint Pupil

Pontine Pathology

oPioids

3- Features of Scleroderma, local and systemic (CREST)

Calcinosis

Raynaud’s phenomenon

Esophageal dysmotility

Sclerodactyly

Telangiectasia